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Basic research

Scarpini E, Galimberti D, Baron PL, Clerici R, Ronzoni M, Conti G, Scarlato G. IP-10 and MCP-1 levels in CSF and serum from multiple sclerosis patients with different clinical subtypes of the disease. Journal of the Neurological Sciences 2002;195:41-46.

Piccio L, Rossi B, Scarpini E, Laudanna C, Giagulli C, Issekutz AC, Vestweber D, Butcher EC, Constantin G. Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors. Journal of Immunology 2002;168(4):1940-9. 

Battistini L, Piccio L, Rossi B, Bach S, Galgani S, Gasperini C, Ottoboni L, Ciabini D, Caramia MD, Bernardi G, Laudanna C, Scarpini E, McEver RP, Butcher EC, Borsellino G, Constantin G. CD8+ T cells from patients with acute multiple sclerosis display selective increase of adhesiveness in brain venules: a critical role for P-selectin glycoprotein ligand-1.Blood 2003;101(12):4775-82.

Galimberti D, Bresolin N, Scarpini E. Chemokine network in Multiple Sclerosis: role in the pathogenesis and targeting for future treatments. Expert Reviews Neurotherapeutics 2004;4(3):89-103.

Giagulli C, Scarpini E, Ottoboni L, Narumiya S, Butcher EC, Constantin G, Laudanna C. RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing. Immunity 2004;20(1):25-35. 

Scarpini E, Galimberti D. Chemokines and their receptors in multiple sclerosis: from the role in the pathogenesis to the targeting for future treatments. In: “Treatment and Management of Multiple Sclerosis Research”, 2005: 89-105. Novapublishers (Editor: Frank Columbus), 2005.

Galimberti D, Fenoglio C, Clerici R, Comi C, De Riz M, Rottoli M, Piccio L, Ronzoni M, Venturelli E, Monaco F, Poloni M, Bresolin N, Scarpini E. E-selectin A561C and G98T polymorphisms influence susceptibility and progression of Multiple Sclerosis. Journal of Neuroimmunology 2005;165:201-205.

Scalabrini D, Galimberti D, Fenoglio C, Comi C, De Riz M, Venturelli E, Castelli L, Piccio L, Ronzoni M, Lovati C, Mariani C, Monaco F, Bresolin N, Scarpini E. P-selectin glycoprotein ligand-1 variable number of tandem repeats (VNTR) polymorphism in patients with Multiple Sclerosis. Neuroscience Letters 2005; 388: 149-152.

Furlan R, Rovaris M, Martinelli Boneschi F, Khademi M, Bergami A, Gironi M, Deleidi M, Agosta F, Franciotta D, Scarpini E, Uccelli A, Zaffaroni M, Kurne A, Comi G, Olsson T, Filippi M, Martino G. Immunological patterns identifying disease course and evolution in multiple sclerosis patients. Journal of Neuroimmunology 2005;165(1-2):192-200. 

Piccio L, Rossi B, Colantonio L, Grenningloh R, Gho A, Ottoboni L, Homeister JW, Scarpini E, Martinello M, Laudanna C, D'Ambrosio D, Lowe JB, Constantin G. Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII. Journal of Immunology 2005;174(9):5805-13. 

Fenoglio C, Galimberti D, Ban M, Maranian M, Scalabrini D, Venturelli E, Piccio L, De Riz M, Yeo T, Goris A, Gray J, Bresolin N, Scarpini E, Compston A, Sawcer S. SELPLG and SELP single nucleotide polymorphisms in multiple sclerosis. Neuroscience Letters 2006; 394(2): 92-96.

Annunziata P, Giorgio A, De Santi L, Zipoli V, Portaccio E, Amato MP, Clerici R, Scarpini E, Moscato G, Iudice A, Vacca G, Orefice G, Morra VB, Maimone D. Absence of cerebrospinal fluid oligoclonal bands is associated with delayed disability progression in relapsing-remitting MS patients treated with interferon-beta. Journal of the Neurological Sciences 2006;244(1-2):97-102.

Galimberti D, Scalabrini D, Fenoglio C, Comi C, De Riz M, Venturelli E, Lovati C, Mariani C, Monaco F, Bresolin N, Scarpini E. IP-10 haplotypes and Multiple Sclerosis: association and correlation with clinical course. European Journal of Neurology, under review.