Alzheimer’s disease

Alzheimer’s disease is the most common cause of dementia in the elderly population of western countries. From the neuropathological point of view, Alzheimer’s disease was diagnosed in the 50-60% of late onset cognitive impairment cases.

The incidence of the disease is similar in all of the world and is calculated as 3/100.000 new cases in people under 60 years of age, 125/100.000 in people aged >60 years . The prevalence is about 300/100.000 between 60 and 69 years of age , 3.200/100.000 between 70 and 79 years of age and 10.800/100.000 in people aged 80 years or older.

Age is the most important risk factor, but also the gender (the disease is more frequent in female than male, with a ratio about 2:1) and the presence of vascular damage factors (stroke events, cholesterol and atherosclerosis).

Mutations in several genes,  transmitted with autosomal dominant manner, account for about 3% of cases affected by Alzheimer’s disease, whereas the majority of cases is sporadic, likely caused by the interaction of genetic and environmental factors.

Cosa fare

Per maggiori informazioni si può contattare il numero 0255033814 – o inviare un'email a centrouva@policlinico.mi.it

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