- Spinal Muscular Atrophy (SMA)
- Amyotrophic Lateral Sclerosis (ALS)
- Charcot-Marie-Tooth disease type 2A (CMT2A)
- Spinal muscular atrophy with respiratory distress type 1 (SMARD1)
The Neural Stem Cells Lab is one of the research facilities of the Centro Dino Ferrari, University of MilanUniversity of Milan, and is located in the Foundation Ca ‘Granda Ospedale Maggiore Policlinico.
Our research group field is in the development of cellular and molecular therapeutic strategies for neurodegenerative diseases (particularly childhood-onset motor neuron disease – spinal muscular atrophy and spinal muscular atrophy with respiratory distress – or adult as Amyotrophic Lateral Sclerosis) and hereditary neuropathies (Charcot-Marie-Tooth type 2A 2).
The transplantation of stem cells may represent potential therapeutic approaches for neurodegenerative diseases, and in particular for motor neuron diseases. The mechanisms by which the transplantation acts include (in addition to cell replacement), the release of neuroprotective factors produced by transplanted cells.